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Research Faculty

Arshad Ahsanuddin, MD

ASSISTANT PROFESSOR OF PATHOLOGY

Research Interests

Dr. Ahsanuddin’s interests are focused on teaching, and the development of enduring materials that supplement and enhance the classical didactic approach to medical education, using techniques appropriate to virtual learning.

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Mary Beth Babos, PharmD

Professor of Pharmacology
Chair of Pharmacology

Research Interests

Dr. Babos' research is centered on ethnobotany with a focus on economic and medicinal use of Appalachian plants, ethnoveterinary uses of plants, and herb/pharmaceutical interactions.


 

Clarence Colle, PhD

Professor of Microbiology
LMU-DCOM Associate Dean of Preclinical Academic Affairs/Basic Medical Sciences

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Adam Gromley, PhD

Associate Professor of Molecular/Cellular Biology
Director of Research

Research Interests

A hallmark of cancer is the accumulation of genetic abnormalities, many of which arise through improper cell division. These dysfunctional cell divisions can arise from defects in the centrosome, a cellular organelle whose normal function is to ensure proper segregation of chromosomes during mitosis, as well as separation of the newly formed daughter cells. We seek to identify the specific mechanisms by which defective centrosomes lead to cancer by manipulating the protein components of the centrosome. These studies will not only contribute to our understanding of the tumorigenic process, but they also have the potential of uncovering new therapeutic targets.

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Zeynep Gromley, PhD

Associate Professor of Biochemistry
Chair of Molecular Sciences

Research Interests

Dr. Zeynep Gromley is interested in biochemical and kinetic mechanisms by which ubiquitin and ubiquitin-like proteins are conjugated to their target proteins in the regulation of cellular mechanisms, specifically in the context of cell cycle control.

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Sherry Jimenez, EdD, FNAOME

Associate Dean Interprofessional Education and Collaborative Practice
Associate Professor of Medical Education

Research Interests

Dr. Jimenez's research interests lie in the areas of assessment of student learning, curricular improvement, and interprofessional education.

 


 

Adam Kolatorowicz, PhD

ASSOCIATE Professor of Anatomy

Research Interests

Dr. Kolatorowicz's research revolves around the documentation of anatomical variation that can be helpful for clinicians when treating patients and conducting medical procedures. Specific foci include clinical anatomy, skeletal biology, forensic anthropology, and the scholarship of teaching and learning. He employs quantitative and qualitative methods in exploratory and conclusive research designs, including surveys, thematic analysis, geometric morphometrics, photogrammetry, meta-analysis, secondary data analysis, and inferential statistical modeling. Much of Dr. Kolatorowicz's research utilizes whole body donors in the LMU-DCOM Anatomy Laboratory as well as donated skeletal collections at other institutions. Most projects involve graduate/medical student researchers as coauthors and collaborative work with researchers at other institutions. Additionally, he provides consulting in research design and statistical data analysis for faculty, staff, and students pursuing their own research programs.

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Stan Kunigelis, PhD

Professor of Physiology
Director of Math and Sciences Imaging & Analysis

Research Interests

Dr. Kunigelis is interested in ultrastructural analysis of zooplankton morphology, development, and diversity as indices of estuarine health.

 



 

 

Jeffrey Martin, PhD

Associate Professor of Physiology
Associate Dean of Basic Medical Sciences
Chair of physiology

Research Interests

Dr. Martin's research is integrative in nature but focuses primarily on cardiovascular physiology, exercise physiology, and metabolism. A major focus of Dr. Martin's work is on the effects of external pneumatic compression on human physiology in health and disease. Specifically, this includes the effects of external compression applied to the limbs on 1) local and systemic vascular function; 2) skeletal muscle adaptation; 3) glucose handling/metabolism; 4) wound healing; and 5) sports performance and recovery. Additionally, Dr. Martin maintains an active interest in the effects of nutraceuticals in health (ergogenic aids) and disease (therapeutic efficacy).

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Lori McGrew, PhD

Associate PROFESSOR OF PHarmacology

Research Interests

Dr. McGrew's research interests center around anxiety and depression. She has utilized a number of model systems to elucidate signaling pathways including cultured cells, rodents, nematodes and fish. Most recently, she has been exploring the ability of cannabinoid compounds to modulate anxiety in the zebrafish, Danio rerio.


 

Debasis Mondal, PhD

Associate Professor of Microbiology and Infectious Disease

Research Interests

Dr. Mondal obtained his Ph.D. in Microbiology and has been a Faculty in Pharmacology for number of years. His research interests have focused on developing novel strategies in order to enhance the efficacy of both anti-cancer and anti-HIV drugs. Indeed, the selection of multidrug resistance (MDR) and toxicities associated with the long-term use of these agents remain a formidable challenge. One promising approach to increase the efficacy of pharmaceuticals has been their combination with safe phytochemical compounds, such as Curcumin and Sulforaphane. Dr. Mondal's group has shown that the molecular mechanism(s) associated with this increased efficacy is the induction of oxidative stress and ER-stress signaling pathways. In addition, Dr. Mondal's group has carried out studies to understand the role of 'Exosomes' in disease progression. Exosomes are lipid nanovesicles carrying mRNA, miRNA and proteins, and are chronically secreted by both aggressive cancer cells and HIV-infected cells. Indeed, the deleterious cargo of Exosomes are being linked to the pathogenesis of numerous chronic diseases. Dr. Mondal's group is investigating whether select pharmaceuticals and/or phytochemicals can suppress Exosome secretion. It is envisioned that adjunct therapy with these Exosome-inhibitory agents may suppress disease progression/pathogenesis in both Cancer and AIDS patients.

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Dominic Palazzolo, PhD

Professor of Physiology

Research Interests

The electronic cigarette (ECIG) phenomenon has taken a strong foothold in twenty-first century culture and is most likely is here to stay. Yet, because of the paucity of empirical research and the controversial data presented, the effects of ECIG generated aerosol on human health remains inconclusive. To better understand how ECIG generated aerosol interacts with biological systems our research focuses on the physical characteristics and chemical composition of the inhaled aerosol concerning the potential dangers of this addictive behavior. A few questions that we are addressing include the following. 1) How does inhaling aerosol derived from different formulations of E-liquids impact human health? 2) What are the relative dangers of inhaling aerosol generated by alternative ECIG design? 3) Does puffing topography based on user experiences and preferences play a significant role in how ECIG generated aerosol affects human physiology? 4) How does the aerosol generated by these ECIGs and E-liquid formulations ultimately affect the ability to effectively deliver nicotine?

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Syed Quadri, PhD

Associate Professor of Pharmacology

Research Interests

Dr. Quadri's research is focused on discovering and identifying novel molecular mechanisms and therapeutic targets by combining unique interdisciplinary knowledge and skills particularly in pharmacology and molecular biology to make contributions to the prevention or treatment of renal inflammation and dysfunction associated with hypertension, obesity and diabetes. He is particularly interested in investigating the role of the prorenin receptor (PRR) and the angiotensin type I (AT1) receptor in modulating renal sodium and water homeostasis and blood pressure regulation.

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Brent Thompson, PhD

Associate Professor of Anatomy

Research Interests

Dr. Thompson's research uses obese cadavers to develop innovative ways to teach about obesity in the medical curriculum.

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Jun Wang, MD, PHD

Associate Professor of Pathology

Research Interests

Dr. Wang's research utilizes breast cancer and prostate cancer cell lines to understand how cell adhesion molecules and their associated signaling pathways regulate the cell adhesion, migration, and invasion of cancerous cells.

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Jan Zieren, DO, MPH

PROFESSOR OF Family Medicine
Medical director, student health center

Research Interests

Dr. Zieren has sponsored student driven research with a Public Health focus in rural or Appalachian settings.