LINCOLN MEMORIAL UNIVERSITY

SCHOOL of NURSING and ALLIED HEALTH

MEDICAL TECHNOLOGY PROGRAM

 

MEDT 462:   Medical Microbiology II

3 Credit Hours       Spring Semester

 

 

INSTRUCTOR:         Mark Camblin, Ph.D., SM (ASCP), SM (NRM)

                                    St. Mary’s Health System Laboratory

                                    Knoxville, TN  37917     Telephone:  (865) 545-7649

                                    Conference Time:   Instructor will be available for

                                    30 minutes after class as needed for student conference.

 

 

PREREQUISITE:      MEDT 461—Medical Microbiology I

 

 

COREQUISITE:        MEDT 492—Advanced Clinical Practice II

 

 

COURSE DESCRIPTION:  MEDT 462 focuses on characteristics of medically important bacteria, anaerobes, mycobacteria, fungi, viruses, and parasites of man.  Includes principles of isolation, identification, and antibiotic susceptibility testing.  The pathogenesis of organisms and host response are included also.

 

 

TEXTBOOKS:           Mahon, C. & Manuselis, G.  (2000).  Textbook of Diagnostic                                       Microbiology, 2nd  Edition.  Philadelphia:  W.B. Saunders

                                    Company.

 

                                    Delost, Maria D.  (1997).   Introduction to Diagnostic                                                   Microbiology:  A Text and Workbook.  St. Louis:  C.V. Mosby

                                    Company.

                                                               

 

METHODS OF INSTRUCTION:  There will be lectures, assigned readings, case studies, class discussions, and clinical correlations.     

 

 

COURSE OBJECTIVES:  Upon completion of MEDT 462, the student will be responsible for attaining the following objectives:

 

1.  Carefully study the assigned chapters in the textbook, and come to class prepared

       to discuss the topics of the day, as indicated on the Lecture Outline.

 

2.  Apply results of biochemical tests, gram stain, and culture appearance to identify the

     anaerobic bacteria studied in this class, to include Clostridium, Peptostreptococcus,

     Peptococcus, Bacteriodes, Prevotella, Porphyromonas, and Veillonella.

 

3.  Discuss the application of the following stains and be able to interpret results:   

     Kinyoun, Ziehl-Neelsen, Lactophenol Cotton Blue, India Ink, and Trichrome stain.

                                                                                                                        MEDT 462

                                                                                                                                                                Page 2

 

4.  With regard to the bacteria and the Mycobacteria studied in this class, be able to   

      describe and discuss the following:

 

                        Morphology                               Staining  Characteristics

                        Nomenclature                           Related  Biochemical  Tests

                        Culture  Requirements               Related  Serological  Tests

                        Colony  Characteristics              Special  Characteristics

 

5.  Be able to differentiate among the species of Mycobacteria by applying results of    

     biochemical tests and colony appearance.

 

6.  Be able to identify Nocardia based upon special stains, colony morphology, and     

     biochemical tests.

 

7.  For each of the following organisms, denote a site in the body where infection typically

     occurs, and describe the symptoms of an infectious disease produced by each.

 

                        Mycoplasma                    Bacteriodes                          Veillonella                 

                        Chlamydia                       Clostridia                             Leptospira           

                        Mycobacteria                  Peptococcus                                    Borrelia              

                        Nocardia                         Peptostreptococcus              Treponema          

 

 8.  For each group of organisms listed above, select appropriate culture methods, media,

       stains or other mechanisms to help identify and differentiate each.

 

 9.  With regard to fungi and yeasts, be able to describe the following:

 

       a.  Germ tube reaction of Candida albicans

       b.  Dimorphism of Histoplasma, Blastomyces, and Coccidiodes

       c.  Use of  Sabouraud and Mycosel agars, and ingredients in each.

 

10.  Apply microscopic morphology, colony appearance, and biochemical tests to identify

       the medically important fungi and yeasts, including  Histoplasma, Blastomyces,

       Cryptococcus, Candida, Coccidiodes, and Aspergillus.

 

11.  Be able to differentiate the dermatophytes from the systemic dimorphic fungi.

 

12.  Recall the scientific name and common name of each parasite studied in this class.

 

13.  By microscopic morphology, identify the ameba, ova, larva, and cysts of parasites

       that commonly infect humans--as indicated by the instructor.

 

14.  Correlate parasitic disease with patients’ symptoms and laboratory findings.

 

15.  Discuss the pathophysiology and serologic diagnosis of viral infection caused by the

       medically important viruses, as indicated by the instructor.

 

         

                                                                                                                                               

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                                                                                                                                                                Page 3

 

EVALUATION  METHOD:

 

There will be three written exams and a comprehensive final exam in this class.  A detailed lecture outline with tentative exam dates is appended at the end of this syllabus.  To enhance understanding of the subject matter, there will be some quizzes and/or homework assignments.  The overall grade will be determined as follows:

 

       3 Written Exams                            65 %  of  grade

       Comprehensive Final Exam            25 %  of  grade

       Quizzes/ Homework                      10 %  of  grade

 

Grading scale is:            A         =          90 -100%

                                    B+       =          87 - 89 %                      Medical Technology students

                                    B          =          83 - 86 %                      must maintain an average of

                                    B-        =          80 - 82 %                      80% or higher in order to pass                                              C+            =          77 - 79 %                      this course.

                                    C          =          73 - 76 %

                                    C-        =          70 - 72 %

                                    D         =          60 - 69 %

                                    F          =          below 60 %

 

Students are strongly advised to attend all lectures.  This senior-level class meets only once per week, but success in this class requires the discipline to study throughout the week--not just the night before class.

 

All students are expected to take exams as scheduled.  If a student misses an exam due to certifiable illness or a death in the family, a make-up exam will be offered by appointment only.  The format of the make-up exam is at the instructor’s discretion.  The university’s policy on academic integrity as stated on page 39 of the LMU Undergraduate Catalog 2003-2004 will be strictly applied in this class.

 

 

UNITS OF INSTRUCTION: 

                                                                                             Textbook Reading Assignment:

 

Lecture 1                      Anaerobes                                                                Chapter 19          

1-14-04          

 

Lecture 2                      Spirochetes, Chlamydia, Mycoplasma                       Chapters  20, 21

1-21-04          

 

Lecture 3                      Spirochetes, Chlamydia, Mycoplasma  (continued)

1-28-04

 

Lecture 4                      Exam  #1     (Chapters 19, 20, 21)

2-04-04

                                                                                                                                                                                                                                                                                                                                                    MEDT 462

                                                                                                                                                                Page 4

 

 

                                                                                              Textbook Reading Assignment:

 

Lecture 5                      Mycobacteria and Nocardia                             Chapters 22, 13

2-11-04

 

Lecture 6                      Mycobacteria and Nocardia  (continued)

2-18-04

 

Lecture 7                      Mycobacteria and Nocardia Enrichment @ SMMC

2-25-04                      

 

Lecture 8                             Exam  #2         (Chapters 22, 13)

3-03-04                      

 

Lecture 9                      Mycology                                                         Chapter 23

3-10-04

 

Lecture 10                    Mycology Enrichment @ SMMC

3-17-04          

 

3-24-04                        Spring Break 

 

Lecture 11                          Exam  #3         (Chapter 23)

3-31-04                      

 

Lecture 12                    Parasitology                                                      Chapter 24

4-07-04          

 

Lecture 13                    Parasitology      (continued)                                             

4-14-04

 

Lecture 14                    Virology                                                           Chapter 25

4-21-04

 

4-28-04                       Comprehensive Final Exam      (Chapters 13, 19 through 25)

 

         

Thursday, 5-06-04       PINNING CEREMONY  @ 6:00 PM             Congratulations!

 

Saturday, 5-08-04       COMMENCEMENT                                       Congratulations!        

 

 

 

 

 

DATE OF REVISION:         January, 2004