SYLLABUS

 

I.              Chemistry 221-222, Organic Chemistry, 3 credit hours per semester.

II.           Fall 2000-Spring 2001.

III.         Instructor:

Dr. Gabriel Otiko

Room: Farr-Chinnock 104

Office Phone: 869 6224

Office Hours: MWF : 8.00am-9.00am;TR  9.00am-10.00am

e-mail: gotiko@inetlmu.lmunet.edu

IV.        Course Prerequisite/Co-Requisite: Chemistry 111-112 and labs.

V.           Course Description: A study of the principles of organic chemistry: Atomic structure, chemical bonding,molecular structure, stereochemistry, reactions  and synthesis.

VI.        Goals: 1) To give students an introduction to organic chemistry. 2) To help them gain the self confidence and discipline necessary to study a difficult subject. 3) To deliver an in-depth survey of organic chemistry. 4) To introduce students to the use of spectroscopy.

VII.      Relationship of this course to content area knowledge and skill: Organic chemistry is a subject required for the study of a number of subjects: chemistry, biology, physics, engineering, secondary education, and certain health related fields. It is a course for students that have had one year of general chemistry, and is intended for students pursuing a career in the sciences, engineering, or health professions.

VIII.   Texts: 1) Wade,L.G. “Organic Chemistry, 4th edition”, Prentice-Hall, 1999. 2) Hehre, W.G. et al., The Molecular Modeling Workbook for Organic Chemistry, Wave function, 1998.

IX.        Course Objectives: 1)To develop students’ understanding of chemical bonding. 2) Study classes organic compounds. 3) Study the stereochemistry of organic molecules.  4) Study the different mechanisms of organic reactions. 5) Study synthetic methods. 6) Discuss spectroscopy techniques.

X.           Outline of Course Content/Units of Instruction

A.     Introduction and review:: Atomic Structure, Lewis Structures, bonding models, formal charges, resonance, determination of formulas, and acid base reviews.

B.     Structure and Properties of Organic Molecules: MO theory, pi bonding, hybridization, isomerism, polarity, and classification of organic molecules.

C.     Alkanes: nomenclature, physical properties, structure and stereochemistry of acyclic and cyclic alkanes, their conformations and reactions.

D.     The Study of Chemical Reactions: halogenation of alkanes, mechanism of free radical halogenation,equilibrium, enthalpy, bond energies, kinetic study of  organic reactions, reactive intermediates

E.      Alkyl Halides: substitution and elimination  reactions, nomenclature, physical properties synthesis, factors affecting the rates of substitution and elimination reactions rearrangements, carbocations.

F.      Stereochemistry: Chirality, R and S nomenclature, optical activity, racemic mixtures, optical purity,Fischer projections, diastereomers,multiple chiral centers, meso compounds, resolution of enantiomers,reactions involving chiral molecules.

G.     Alkenes: nomenclature, structure, synthesis, and reactions.

H.     Alcohols: nomenclature, structure synthesis and reactions.

I.        Spectroscopy: The basic principles on which all spectroscopic techniques are based, the types of information that organic chemists can obtain from different spectroscopic techniques such as IR, NMR, UV-visible. The principle and the use of Mass spectrometry in organic chemistry.

J.       Ethers and epoxides: nomenclature, synthesis and reactions.

K.    Alkynes: nomenclature, synthesis and reactions.

L.      Conjugated double bonds: orbital symmetry, MO treatment of conjugated systems, reactions of dienes, MO approach to the bonding in allylic systems.

M.   Aromatic systems: Huckel theory, MO treatment of aromatic compounds, aromatic ions, nomenclature and spectroscopy.

N.    Reactions of aromatic compounds: Birch reduction, aromatic electrophilic substitution,  activation and deactivation of the aromatic ring.

O.    Ketones and aldehydes: reactions, synthesis and uses; carbanion reaction, condensation reactions involving enols and enolates , nucleophilic reactions, and deoxygenation reactions.

P.      Carboxylic acids and derivatives:reactions, synthesis and biological uses.

Q.    Amines: nomenclature, structure, spectroscopy, reactions, synthesis, and rearrangements in amine reactions.

R.     The course contents will be the chapter by chapter coverage of the textbook. Any material that will not be covered will be announced by the instructor. The student is responsible for reading each chapter and section even if that material was not covered in class.

XI.              Required Readings: Textbook and  material distributed by the instructor.

XII.            Suggested Bibliography: None.

XIII.         Method of Instruction and Learning: Classroom lecture, problem solving, and homework will be the means  of instruction. Homework will be collected and reviewed. Students will be expected to read assignments before coming to class,

XIV.         Course Requirements/Methods of Assesment/Evaluation/Documentation: All students are expected to attend classes regularly, to complete assignments on time , to study and to work hard. If you choose not to attend class you r are responsible for obtaining any notes and class materials from the instructor, at which time you will be asked for a reason for your absence. If you miss an examination, and the absence is considered inexcusable, you will not be allowed to make up the examination. Examples of inexcusable absences include, but are not limited to: sleeping in, not ready for an examination, did not feel like taking exam, had a hospital clinical the day before and did not have a chance to prepare for the exam, had another exam the day before and did not have a chance to prepare for the exam, had a headache, etc. Excused absences might include death in the family, hospitalization, illness( you will need a doctor’s certificate), etc. This class is scheduled for a 50 minute period. If you come late, you will only have the remainder of the period to finish the examination. There will be an examination after every two or three chapters of material and a comprehensive final examination. The method of assessment (on a per semester basis) is as follows:

3 examinations                      300 points

Final examination                  200 points

Total                                       500 points

90% and above                                      A

80%-89%                                               B

70%-79%                                               C

60%-69%                                               D

< 60%                                                     F

      + Grades will be assigned to any student in the upper 20% bracket of any grade group

      - Grades will be assigned to any student in the bottom 30% bracket of any grade grou

XV,  Laboratory Work: The instructor will give the assignments.

XVI. Date of last revision: August 24 2000.